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Protein separations – 17% of total Amersham sales
Chromatography purification systems, membrane products and media used in the manufacture of biopharmaceuticals (any biologically-derived drug, eg. insulin, vaccines, DNA-based medicines, monoclonal antibodies, interferon), and for the laboratory scale separation of proteins for research and drug development.

Discovery systems – 24% of total Amersham sales
High throughput systems (instruments, reagents, software) for genomics (DNA sequencing, gene expression and gene variation), proteomics (study of proteins and their role in biological function), and bioassays (analysis of cellular processes in metabolism and disease, used for screening and testing of potential new drugs).

Performance 2002
Sales
£670 million,
up 6%
Operating profit
£75 million,
flat*
R&D expenditure
£88 million,
up 3%

Employees
4,650
*Up 9% excluding the £8 million dilutive impact of the CodeLink™ and Cimarron acquisitions.

Protein separations – key platforms

Bioprocessing – columns
Bioprocessing – separations media
  Bioprocessing – columns
Our bioprocess systems (instruments, media and software) are used by leading pharmaceutical and biotech companies for the industrial manufacture of over 90 per cent of the biopharmaceuticals on the market or in development. The wide range of chromatography columns includes Chromaflow™ and Streamline™ brands.
Bioprocessing – separations media
Consumables used in bioprocessing. Leading brands include Sepharose™, MabSelect™, and Source™.
 
 

 

 

     
Bioprocessing – membrane separation
Laboratory separations
  Bioprocessing – membrane separation
Hollow fibre filtration membranes used in bioprocessing – an essential step for removing impurities in biologically-based drugs.
Laboratory separations
ÄKTA™ platform – the gold standard in chromatography systems for laboratory purification of proteins before scale-up to manufacturing.
 
 

 

 

     
Discovery systems– key platforms

 
Genomics
Bioassays
  Genomics
DNA sequencing: MegaBACE™ DNA sequencer for decoding the genetic structure of human, animal and plant species. TempliPhi™ template preparation kit for producing DNA samples. Gene expression: CodeLink™ pre-arrayed slides and Lucidea™ custom slides platform, on which thousands of DNA samples are scanned to identify differences in the way genes are expressed.
Bioassays
Instruments include LEADseeker™, which has the ability to screen up to 1,000,000 new drug compounds a day, and IN Cell Analyzer, which enables scientists to study the effects of a potential new drug on living cells in real time. Products also include a range of custom-labelled reagents for toxicology testing.
 
 
Proteomics
Informatics
  Proteomics
Ettan™ high throughput protein analysis platform utilising systems such as mass spectrometry and electrophoresis to identify and characterise proteins, and to compare protein expression in diseased and normal tissues, enabling drugs to be targeted to diseases. Products also include the CyDye™ range of fluorescent dyes.
Informatics
Scierra™ platform of software solutions for managing and organising the vast amounts of data being generated in life sciences research.
 
 
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