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| Chromatography purification systems, membrane
products and media used in the manufacture of biopharmaceuticals
(any biologically-derived drug, eg. insulin, vaccines, DNA-based
medicines, monoclonal
antibodies, interferon),
and for the laboratory scale separation of proteins
for research and drug development. |
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High
throughput systems (instruments, reagents, software) for
genomics
(DNA sequencing,
gene expression and gene variation), proteomics
(study of proteins and their role in biological function), and
bioassays
(analysis of cellular processes in metabolism and disease, used
for screening and testing of potential new drugs).
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Sales
£670 million,
up 6% |
Operating profit
£75 million,
flat* |
R&D expenditure
£88 million,
up 3%
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Employees
4,650 |
| *Up 9% excluding the £8
million dilutive impact of the CodeLink and Cimarron acquisitions. |
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Bioprocessing – columns
Our bioprocess
systems (instruments, media and software) are used by leading
pharmaceutical and biotech companies for the industrial manufacture
of over 90 per cent of the biopharmaceuticals on the market
or in development. The wide range of chromatography
columns includes Chromaflow™ and Streamline™ brands. |
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Bioprocessing – separations
media
Consumables used in bioprocessing. Leading brands include Sepharose™,
MabSelect™, and Source™. |
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Bioprocessing – membrane
separation
Hollow fibre filtration membranes used in bioprocessing – an
essential step for removing impurities in biologically-based
drugs. |
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Laboratory separations
ÄKTA™ platform – the gold standard in chromatography systems
for laboratory purification of proteins before scale-up to manufacturing. |
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Genomics
DNA sequencing: MegaBACE™ DNA sequencer for decoding the genetic
structure of human, animal and plant species. TempliPhi™ template
preparation kit for producing DNA samples. Gene expression:
CodeLink™ pre-arrayed slides and Lucidea™ custom slides platform,
on which thousands of DNA samples are scanned to identify differences
in the way genes are expressed. |
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Bioassays
Instruments include LEADseeker™, which has the ability to screen
up to 1,000,000 new drug compounds a day, and IN Cell Analyzer,
which enables scientists to study the effects of a potential
new drug on living cells in real time. Products also include
a range of custom-labelled reagents for toxicology
testing. |
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Proteomics
Ettan™ high throughput protein analysis platform utilising systems
such as mass
spectrometry and electrophoresis
to identify and characterise proteins, and to compare protein
expression in diseased and normal tissues, enabling drugs to
be targeted to diseases. Products also include the CyDye™ range
of fluorescent dyes. |
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Informatics
Scierra™ platform of software solutions for managing and organising
the vast amounts of data being generated in life sciences research. |
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