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Giles Kerr

2001 has proved to be another excellent year for Amersham, showing our resilience to difficult economic conditions, with strong growth in sales and double-digit growth in earnings per share. Our sales have exceeded £1.6 billion pounds for the first time.

In September 2001 we sold our remaining 29 per cent stake in Nycomed Pharma. We received sales proceeds of £73 million and realised £50 million for the outstanding Nycomed Pharma loan note held by the group. A profit was recorded on the transaction of £55 million after associated costs, which included the costs of transferring the Nycomed name to Nycomed Pharma and our consequent name change from Nycomed Amersham to Amersham plc. Following on from the sale of the majority stake in May 1999, our total cash proceeds are now £399 million for the Nycomed Pharma business as a whole and we have recorded a total profit of £57 million before taxation.

Cash flow this year has been particularly strong with excellent cash generation from our business operations in addition to the sale of the 29 per cent stake in Nycomed Pharma. We have used these funds to reduce our net debt by almost £300 million so that at the year end net debt stands at £25 million. Since the year end we have signed a new $750 million syndicated bank credit facility committed to February 2007 to replace the previous facility which was due to mature in September 2002.

Results overview
Sales during 2001 were £1,603 million, up 13 per cent at constant exchange rates, excluding the impact of disposed businesses. The strong sales growth was balanced across both businesses with Amersham Health up 13 per cent year on year and Amersham Biosciences up by 12 per cent. Our businesses continue to benefit from the geographical breadth and robustness of their market positions with double-digit growth recorded in both the patented and unpatented product portfolio of Amersham Health and in the separations and proteomics businesses of Amersham Biosciences. Together these account for 60 per cent of our total sales.

Operating profit before exceptional items and goodwill amortisation was £293 million. This is eight per cent higher than last year and is after a £25 million (16 per cent) growth in our R&D expenditure. Total trading profit before R&D costs and exceptional items and goodwill amortisation is £466 million, up 11 per cent from last year. The continued investment in R&D reflects our strong commitment to the development of the product portfolio. In Amersham Health we have taken new initiatives in life-cycle projects, partnerships and in-licensing, as well as continuing internal R&D. In Amersham Biosciences, we have continued the trend seen over the last three years of significant investment in R&D, which grew by 22 per cent this year, to build up a substantial portfolio of products and to incorporate new technologies particularly in genomics, proteomics, bioassays and the rapidly growing separations business. Having brought several major new product platforms to market since 1998 we have now completed a phase of significant investment, and in the second half of 2001 R&D investment was slightly lower than in the first half year.

Interest costs have been reduced this year, due to a significant reduction in our net debt following strong cash flow including the sale of our remaining stake in Nycomed Pharma. We have also taken a charge of £4 million against the carrying value of listed investments following a material reduction in their market value during 2001. We hold a small number of equity positions in companies with which we have collaboration agreements, with the total value of our trade investments at year end standing at £14 million.

Profit before tax was £279 million before exceptional items and goodwill amortisation, up from £231 million last year, and included a favourable exchange rate impact of £26 million, resulting primarily from the strengthening of the US dollar. Overall profit before tax (including exceptional items and goodwill amortisation) was £314 million, up from £194 million in 2000.

The group’s underlying tax rate, before exceptional items and goodwill amortisation, was 33.1 per cent (34.6 per cent after goodwill amortisation), a reduction of 0.9 per cent from last year. The rate is lower principally as a result of the favourable settlement of a number of outstanding tax items relating to earlier years. Earnings per share were 27.2p before exceptional items and goodwill amortisation, compared with 22.5p last year, representing a growth of 21 per cent at actual exchange rates and 10 per cent at constant exchange rates. We paid an interim dividend of 2.35p per share and the Board is recommending a final dividend of 4.75p per share, bringing the total dividend to 7.10p for the year, an increase of 11 per cent.

We have realised a pre tax exceptional profit this year of £47 million. Included within the £47 million is the £55 million profit generated by the sale in September 2001 of our remaining 29 per cent stake in Nycomed Pharma. Exceptional operating costs incurred in 2001 totalled £9 million compared to £27 million in 2000. During 2000, £10 million of exceptional operating costs were incurred in disengaging from the Nycomed Pharma business following the initial sale of 71 per cent of the business in May 1999. In 2001, costs of £3 million have been incurred in relation to the proposed partial flotation of Amersham Biosciences announced last year and currently on hold as a result of market conditions. The company received £23 million related to a transfer of assets from former pension plans, with £9 million recorded as exceptional operating income after providing for ongoing liabilities, primarily for employees who have transferred into the Amersham plc pension scheme. Costs of £6 million were incurred in concluding and winding up the operation of an early stage investment in disease profiling research. Costs of £9 million for asset write offs and decommissioning have been recorded in relation to the decision to terminate our lease at Harwell following a complete cessation of the company’s activities on that site.

Overall, basic earnings per share, after exceptional items and goodwill amortisation, have increased from 17.6p in 2000 to 33.9p in 2001.

Financial Reporting Standards
During 2001 we implemented Financial Reporting Standard (FRS) 18 ‘Accounting Policies’, and have included the relevant disclosure requirements of FRS 17 ‘Retirement Benefits’.

On the introduction of FRS 18 the group changed its accounting policy in relation to revenue recognition on Technology Transfer agreements to recognise associated revenue evenly over the life of the agreement in order to provide greater comparability between different arrangements. In accordance with FRS 18 we have restated prior years to recognise this accounting policy change, the full details of which are contained in note 36 to the financial statements.

FRS 17 will change the way that companies account for pensions and other retirement benefits. The standard is applicable for accounting periods ending after 22 June 2003, although we are now in a transition period when additional disclosures are required, which are contained in note 29 to the financial statements.

We are required to adopt FRS 19 ‘Deferred Taxation’ in 2002. We do not anticipate that this will have any significant impact on either our underlying tax rate or the group’s balance sheet.

Cash flows and investment activities

  2001
£m

2000
£m
 
Cash flow from operations before exceptional items 342   255  
Business reorganisation and exceptional items        
Integration and exceptional items 12   (31 )
Disposals and sales of assets 23   11  
  35   (20 )
Business investments        
Capital expenditure (102 ) (128 )
Acquisitions and purchases (14 ) (38 )
  (116 ) (166 )
Business cash flow 261   69  
Proceeds from disposal of Nycomed Pharma 123    
Interest, tax, dividends and share capital (79 ) (62 )
Net cash flow before repayment of debt 305   7  

Cash flow has been particularly strong during 2001 with cash flow from operations before exceptional items £87 million higher than in 2000. We generated £35 million from business reorganisation and exceptional items including the £23 million received from the transfer of assets from former pension plans. The overall level of business investment has reduced this year, with capital expenditure £26 million lower than 2000 following the completion of our rationalisation of manufacturing and other operations after the 1997 mergers. Business cash flows increased from £69 million in 2000 to £261 million in 2001.

Net cash flow before repayment of debt was £305 million, an increase of £298 million compared to 2000. These funds have been used to reduce our net debt by £298 million, after an exchange impact of £7 million. Net debt stands at £25 million at 31 December 2001. The cash flow generated by our businesses is analysed in the following table:

  2001
£m

2000
£m
 
Business cash flows        
Amersham Health 174   106  
Amersham Biosciences 84   (8 )
Corporate 3   (29 )
Business cash flow 261   69  

Our Amersham Health business continues to generate strong cash flow for the group with £174 million realised during 2001, an increase of £68 million over last year. Amersham Biosciences also generated good cash flow in the year following lower capital expenditure and a strong improvement in working capital whilst continuing the growth in R&D investment. Cash flow in 2001 was £84 million compared with a cash funding of £8 million in 2000. Corporate cash flow includes the funds from former pension plans noted above as well as corporate costs.

Treasury policy and liquidity
Treasury policy and objectives

Our treasury activities are co-ordinated and managed by the group treasury department in accordance with policies approved by the Board. These policies are reviewed regularly and have not changed significantly over the past year. The department operates under close management supervision and is subject to review by the Risk and Operational Review department. It does not operate as a profit centre and no speculative transactions are undertaken.

Financial instruments
The group uses financial instruments, primarily forward foreign exchange contracts and interest rate swaps, in the management of currency and interest rate exposures. Clear procedures have been established, including levels of authority, regarding the type and use of financial instruments to manage these exposures. The Board has approved these procedures. The group controls credit risk by entering into transactions involving financial instruments only with authorised counter-parties of strong credit quality. Counterparty positions are monitored regularly.

Funding
The group requirement for debt funding is managed by group treasury. The group finances its operations through a variety of instruments and maturities. In general, subsidiaries’ borrowing requirements are funded by loans from group treasury, except where precluded by local regulations. The principal borrowings during the period were US$213 million (£152 million) of private placement loan notes and drawings under a £430 million committed revolving bank credit facility. At 31 December 2001, the group had net debt of £25 million with no drawings on the £430 million committed facilities. Since the year end the company has signed a new $750 million syndicated bank facility committed to February 2007 and the previous facility has been cancelled.

Interest rate management
The group’s interest charge is exposed to movements in interest rates as well as debt levels. Our policy is to hold between 30 and 70 per cent of debt at fixed rates. Following the disposal of Nycomed Pharma in August 2001 we repaid all outstanding short term debt and invested the remaining proceeds in short term floating rate based instruments. We continue to carry $213 million (£152 million) of fixed rate private placement notes which mature between 2002 and 2009 and which are uneconomical to repay. At 31 December 2001, after taking into account interest rate swaps, 85 per cent of debt was at fixed rates. The average maturity of this fixed rate debt was 2.4 years. With net debt and interest now at historically low levels and net interest covered over 34 times by operating profit, we will revert to our policy concerning fixed rate debt when debt levels become more significant. The group uses currency and interest rate swaps to manage its interest rate exposures on debt and cash positions. The interest rate profile of the group is shown in note 20 to the financial statements.

Currency management
The group’s manufacturing activities and costs are concentrated in a small number of countries, primarily the US, Norway, Sweden and the United Kingdom. Sales income is spread more widely. Overall we have net income in US dollars, euros and Japanese yen and net costs in sterling, Norwegian kroner and Swedish krona. The group’s principal financial exposures are to movements in currency exchange rates. These comprise transaction exposures arising from currency cash flows and translation exposures arising from the conversion of the results of foreign subsidiaries. Transaction exposures are hedged on a rolling six month basis, primarily by forward foreign exchange transactions. In addition, where sterling has deviated significantly from its long term purchasing power parity rates, strategic hedging is undertaken for periods of up to three years. During the year, we took advantage of the strength of the US dollar by selling forward an increased proportion of our anticipated US dollar income for the next three years in accordance with our strategic hedging policy. Translation exposures on the net monetary assets of foreign subsidiaries are generally hedged by borrowings and deposits with group treasury. An analysis of net monetary assets by functional currency is shown in note 20 to the financial statements. Translation exposures on the results of foreign subsidiaries are not hedged. Equity investments in certain subsidiaries and associated companies are hedged by financial instruments in the currencies of those investments.

In 2001, profit before tax was impacted by a favourable exchange effect of £26 million as a result of the strengthening US dollar, and weakening of the Scandinavian currencies, against the pound.

Introduction of the euro
Following the three year transition period, euro notes and coins were introduced on 1 January 2002. We completed all the changes required to our systems and procedures during 2001 and encountered no problems with the change over.

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Giles Kerr
Finance Director



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